Dimethylglycine, also known as DMG, is a natural substance found in both plant and animal cells, and is derived from the amino acid glycine (see reference 1 under Clinical Summary para 1). As a supplement, it is purported to offer a number of health benefits, from enhancing physical performance to improving behavior in children with autism and attention deficit disorder. However, the evidence to support these claims is lacking, according to the Memorial Sloan Kettering Cancer Center (see reference 1 under Mechanism of Action).
How DMG Works
The body produces DMG in the cells by breaking down choline (see reference 1 under Clinical Summary). https://mtqdkq.weebly.com/blog/ssh-for-mac-download. In the body, it acts as an antioxidant and improves oxygenation of the cells (see reference 1 under Clinical Summary). The thought is that taking DMG as a supplement may further enhance oxygenation, which improves athletic performance (see reference 1 under Clinical Summary). It is also thought to act as a neurological stimulator, which is why it has gained popularity in the autism community (see reference 1 under Clinical Summary). According to an October 2009 review article on the use of complementary medicine in autism published in 'Child and Adolescent Psychiatric Clinics,' the two clinical trials testing the use of DMG on children with autism showed no positive effect or improvement in behavior (see reference 2 under DMG).
Safety Concerns
DMG is considered a safe and non-toxic substance, according to MSKCC (see reference 1 under Clinical Summary). If you're supplementing your diet with DMG, be sure to inform your doctor to monitor for any potential side effects or interactions. Additionally, while it's safe to take DMG, do not rely on it as a cure or treatment for any illness.
With 90% of our kids on the autism spectrum having issues with methylation, which usually result in speech or sensory processing issues, DMG and TMG are great supplements to try. Especially since they have been reported to have a 50% success rate for ASD kids. (read about that here) Now let me tell you about our experience with DMG and TMG.
- Trimethylglycine vs Glycine So I'm taking a few grams of trimethylglycine every couple days. It seems to loosen up any constipation issues I might have and sometimes increases energy levels and libido.
- DMG works far better for me. I find TMG too stimulating. DMG was the first methyl donor I ever tried. I had gone through 3 years of very little sleep, and the sleep I did get was highly interrupted. When I first tried DMG, it was the first time I had yawned in all that time.
Dmg Vs Tmg For Children
Dr. Wong's Essentials® TMG-DMG Plus is a blend of Trimethylglycine (TMG), Dimethylglycine, Yohimbe Bark Extract and Serrapeptidase to help the body make Nitric Oxide; increase vaginal lubrication and clitoral engorgement; and increase the making of strong, large and motile sperm.
Dimethylglycine (DMG) and Trimethylglycine (TMG): Amino acids. Mostly used as an immune modulator to boost immunity, to sharpen thinking and increase attention span and as a methyl donor to the Kreb’s Cycle increasing the production of ATP. In this product these two amino acids are used for what they biosynthesize in the body, which is Nitric Oxide, the blood gas that dilates blood vessels all over the body. The difference in the steps needed to make NO between the DMG and TMG allows for the DMG to produce a faster creation of NO while the TMG takes a step longer and starts later and that prolongs the NO making effects of the product.
Yohimbe, is a known vasodilator which also when taken in high doses of the raw powder or in a concentrate will also increase dopamine production and thus have its well known effect of increasing libido with out increasing testosterone level (2). Dmg 5e pdf. The pharmecutical extract of Yohimbe Yohimbine HCl was the first product approved by FDA for use as an Aphrodisiac. A novel use of Yominbine HCl is to treat PTSD and Social Anxiety Disorder(1).
Serrapeptidase Proteolytic enzymes greatly increase absorption of anything taken with it, vitamins, minerals, herbs, medications, etc. In Europe and Asia, even antibiotics are mixed with proteolytic enzymes (pancreatin or serrapeptidase) to enhance absorption and utilization. With that thought in mind, many of our supplements have been blended with serrapeptidase to enhance absorption.
When the Nitric Oxide increasing effect of the DMG and TMG is combined with the blood vessel dilating effect of the Yohimbe extract, the synergy of the individual ingredients in dilating blood vessels all over the body is enhanced greatly,
Research:
Research on DMG and TMG forthcoming in a book.
Research On Yohimbe:
What Is Tmg Used For
![What What](/uploads/1/3/4/3/134344445/939141238.jpg)
Dmg Vs Tmg Benefits
- https://www.ncbi.nlm.nih.gov/pubmed/23939512